Real-Time Nanoparticle Characterization Through Optofluidic Force Induction

نویسندگان

چکیده

We propose and demonstrate a scheme for optical nanoparticle characterization, optofluidic force induction (OF2i), which achieves real-time counting with single-particle sensitivity, high throughput, particle sizes ranging from tens of nanometers to several micrometers. The particles be analyzed flow through microfluidic channel alongside weakly focused laser vortex beam, accomplishes two-dimensional trapping the in transverse directions size-dependent velocity changes due forces longitudinal direction. Upon monitoring trajectories each individually tracked particle, we obtain detailed information about number-based size distribution. A parameter-free model based on Maxwell’s equations Mie theory is shown provide very good agreement experimental results standardized spherical shape. Our prove that OF2i can flexible work bench numerous pharmaceutical technological applications, as well medical diagnostics.Received 25 April 2022Revised 24 June 2022Accepted 27 2022DOI:https://doi.org/10.1103/PhysRevApplied.18.024056© 2022 American Physical SocietyPhysics Subject Headings (PhySH)Research AreasClassical opticsLight-matter interactionMetrologyMicrofluidicsOptical forcesPhysical SystemsColloidsNanoparticlesSuspensionsAtomic, Molecular & OpticalCondensed Matter, Materials Applied PhysicsFluid DynamicsPolymers Soft Matter

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ژورنال

عنوان ژورنال: Physical review applied

سال: 2022

ISSN: ['2331-7043', '2331-7019']

DOI: https://doi.org/10.1103/physrevapplied.18.024056